I recently read about some research involving psilocybin as a treatment for depression. The results were apparently encouraging.

I know in my own case, I think I may have self-medicated without even realizing it--I took shrooms a few years ago (first and only time) and not long after I gave up antidepressants for Lent. I haven't been back since.

(There were some messy side effects--a panic attack that hit me about a day after the dosage and, oh, falling in love with the man who gave me the shrooms, but I think those trade-offs were ultimately worth it.)

Given the severity of Paul's situation, I think he may well need more extreme solutions than what I took. I wish you well on your journey.